Vacature

Reduced exercise capacity and post-exertional malaise (PEM) are hallmark symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), but the underlying causes are still not fully understood. The main goal of this project is to gain deeper insight into the muscle abnormalities linked to exercise limitations and PEM, with the aim of improving patients’ quality of life. The PhD candidate will analyze existing data from Harvard Medical School to investigate the connection between different types of exercise limitations and muscle changes. Additionally, you will collect new data using non-invasive techniques like magnetic resonance imaging (MRI) and near-infrared spectroscopy (NIRS) to study muscle changes in patients with ME/CFS and healthy individuals. This will help to develop these non-invasive measurements and assess their utility for detecting muscle changes in clinical research and care.